List of UNESCO Chairs and UNITWIN Networks in Natural Sciences in South Africa:
- UNESCO Chair in Technological Entrepreneurship (684) - Tshwane University of Technology - established in 2005.
- UNESCO Chair in Geohydrology (426) - University of the Western Cape - established in 1999.
- UNESCO Chair in Biotechnology (449) - University of Limpopo - established in 1999.
- UNESCO Chair in Mathematics and Science Education (213) - University of Western Cape, within the framework of UTRECHT-UNITWIN Network for Southern Africa - established in 1992.