UNESCO Ethics of Science and Technology Programme was created in 1998 with the establishment of the World Commission on the Ethics of Scientific Knowledge and Technology (COMEST) to give an ethical reflection on science and technology and its applications.

UNESCO’s Ethics of Science and Technology Programme aims to promote consideration of science and technology in an ethical framework by initiating and supporting the process of democratic norm building. This approach is founded upon UNESCO's ideal of "true dialogue, based upon respect for commonly shared values and the dignity of each civilization and culture". Awareness raising, capacity building and standard-setting are therefore the key thrusts of UNESCO's strategy in this and all other areas.