Carlos J. Finlay

Last update:16 May 2023
Black and white photo of Carlos J. Finlay

Born on 3 December 1833 in Puerto Príncipe (today's city of Camagüey) in a French-Scottish family, Carlos J. Finlay studied at some of the most prestigious schools and institutes in the world.

After receiving his primary education at home, his parents sent him to France to pursue his studies. His father was a renowned doctor and physician in Cuba, and he also chose medicine.

However, diseases and political troubles affecting Europe at that time obliged him to go back home repeatedly, then to leave France in order to continue his studies in Germany, the United Kingdom, and ultimately the United States. He finally graduated in medicine at the Jefferson Medical College of Philadelphia, on 10 March 1855.

In Philadelphia, he befriended his professors and mentors John Kearsly Mitchell and his son Silas Weir Mitchell. The ywere both both distinguished academicians and partisans of the germ theory of disease. Today this theory cis one of the founding principles of modern medicine as well as of clinical microbiology, but at that time it was still at the experimental stage. It postulates that several diseases result from the contamination of the body by external microorganisms.

The Mitchells wished to see their brilliant disciple embarking on his medical career in the United States, but Finlay wanted to go back to his natal island and work beside his father. After eight years of travels and specialization courses abroad, in 1864 he finally began practicing as a doctor in La Havana.

Here, his profession brought him face to face with epidemics periodically ravaging his country: malaria, yellow fever, cholera and others. Little was known about these plagues origins and transmission, making them all the more merciless. Finlay decided to focus his research on these diseases, in order to fill the scientific knowledge gaps about them.

He first developed a new theory on cholera, as his research had persuaded him that this disease is transmitted by water. However, this thesis remained disregarded by the scientific community. Then, he started focusing on yellow fever, which was causing huge human and economic losses in the Americas and especially in Cuba.

On 14 August 1881, Finlay presented at the Royal Academy of Medical, Physical and Natural Sciences of Havana a work titled “The Mosquito Hypothetically Considered as the Transmitting Agent of Yellow Fever”. In this paper, he first asserted the hypothesis that the mosquito Culex fasciatus, currently named Aedes aegypti, is the agent transmitting yellow fever. Yet, this thesis as well was rejected/disdained by academicians. The peers of Finlay considered it fanciful, but actually it was just too revolutionary for the scientists. At that time in fact, the idea of insect vectors of diseases in itself was still ahead of its times.

Since 1881, Finlay carried out several hundreds of experiments on people who voluntarily exposed themselves to the bite of infected mosquitos Aedes aegypti. Unfortunately, very few trials succeeded, because, even Finlay's intuition was correct, his methodology for the experiments was not. Thus, the inconstancy of his empirical results was more and more reinforcing the opinions rejecting, and even ridiculing him.

During the Spanish-American war this disease killed more people than the conflict in itself. Hence, the US Army sent Walter Reed's team of Reed to Cuba in order to find a remedy. Finally, they succeeded in proving the validity his theory.

At first, Americans doctors greeted Finlay's mosquito theory with scepticism, but soon they resolved to appeal for his aid. Finlay demonstrated to have a great spirit of scientific solidarity in furnishing them his infected samples of Aedes aegypti along with his assistance. This collaboration enabled them to make a great leap forward in scientific research and save millions of lives.

Reed was wrongly credited as the discoverer of the way yellow fever was spread. Yet, the American doctor has always given credit to Finlay. When he died, Finlay was highly esteemed amongst the scientific community as well as by the public administration of Cuba. Pioneer of the struggle against yellow fever and precursor of the theory of biological vectors of diseases, he was a great innovator of medical science. Furthermore, he held few positions of high responsibility within the public health system of his country.

Throughout his career, he was awarded several prizes and honours by scientific institutions all around the world. Many institutes, streets and places in the world were named after him and, after his death, the Pan American Health Organization declared his birthday, the 3rd of December, as Medicine Day in Latin America.